BDBM227609 (E)-5-chloro-N'-(2,4,5-trihydroxybenzylidene)-1H-indole-2-carbohydrazide (10)

SMILES Oc1cc(O)c(\C=N\NC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1O

InChI Key InChIKey=MTKYCXWUJSYIMK-CNHKJKLMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 227609   

TargetBeta-glucuronidase(Homo sapiens (Human))
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM227609((E)-5-chloro-N'-(2,4,5-trihydroxybenzylidene)-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM227609((E)-5-chloro-N'-(2,4,5-trihydroxybenzylidene)-...)
Affinity DataIC50:  500nMAssay Description:β-glucuronidase activity was determined in accordance to method used by Taha et al. [Taha et al., Bioorg. Med. Chem., 23:7394-7404] by measuring...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails