BDBM23719 4-bromo-1-[(2-chloro-4,5-difluorophenyl)carbonyl]-1H-pyrazole::N-Benzoylpyrazole deriv., 27
SMILES Fc1cc(Cl)c(cc1F)C(=O)n1cc(Br)cn1
InChI Key InChIKey=SSRIKTAQJWMPPG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 23719
Affinity DataKi: 7.20E+3nM ΔG°: -7.01kcal/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataAssay Description:Thrombin activity was monitored at excitation and emission wavelengths of 355 and 460 nm, respectively. For all compounds tested, the concentration o...More data for this Ligand-Target Pair
Affinity DataAssay Description:Cathepsin D assays were monitored with a Fluoroskan Ascent FL microtiter plate reader at excitation and emission wavelengths of 340 and 390 nm, respe...More data for this Ligand-Target Pair
Affinity DataAssay Description:Kallikrein activity was monitored at excitation and emission wavelengths of 355 and 460 nm, respectively. For all compounds tested, the concentration...More data for this Ligand-Target Pair
Affinity DataAssay Description:Reactions for aminopeptidase M activity were monitored at 405 nm using a SpectraMax Plus microplate reader. For all compounds tested, the concentrati...More data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Chymotrypsin activity was monitored at excitation and emission wavelengths of 355 and 460 nm, respectively. For all compounds tested, the concentrati...More data for this Ligand-Target Pair
Affinity DataIC50: 2.83E+4nMAssay Description:Urokinase activity was monitored at excitation and emission wavelengths of 355 and 460 nm, respectively. For all compounds tested, the concentration ...More data for this Ligand-Target Pair