BDBM241609 US9409915, 103::US9718820, Compound 103

SMILES COc1nc(cc2nc(-c3c(Cl)c(nn3C)C(C)(C)C)n([Na])c12)-c1c(Cl)cccc1Cl

InChI Key InChIKey=PXPCKSAPWJMADV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 241609   

TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM241609(US9409915, 103 | US9718820, Compound 103)
Affinity DataIC50:  5.40nMT: 2°CAssay Description:HEK293 cells stably expressing canine TRPM8 were routinely grown as monolayers in Dulbecco's minimum essential medium supplemented with 10% FBS, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential M8 protein(Canis lupus familiaris (Dog))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM241609(US9409915, 103 | US9718820, Compound 103)
Affinity DataIC50:  5.40nMT: 2°CAssay Description:HEK293 cells stably expressing canine TRPM8 were routinely grown as monolayers in Dulbecco's minimum essential medium supplemented with 10% FBS, 2 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent