BDBM244151 US9428492, 20::US9428492, 20a::US9428492, 20b

SMILES Cc1nc(C(O)C(F)(F)F)n(n1)-c1cc(nc(C)n1)C1C[C@H]1c1nc2ccccc2n1C

InChI Key InChIKey=AZVXNJWTMXGGSL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 244151   

LigandPNGBDBM244151(US9428492, 20b | US9428492, 20a | US9428492, 20)
Affinity DataKi:  0.550nM ΔG°:  -12.6kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

LigandPNGBDBM244151(US9428492, 20b | US9428492, 20a | US9428492, 20)
Affinity DataKi:  0.580nM ΔG°:  -12.6kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

LigandPNGBDBM244151(US9428492, 20b | US9428492, 20a | US9428492, 20)
Affinity DataKi:  0.920nM ΔG°:  -12.3kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent