BDBM259854 US9505766, 58
SMILES Nc1ncnc2n(cc(-c3ccc(Oc4ccccc4)cc3)c12)-c1cccc(\C=C(/C#N)C(=O)N2CC(O)C2)c1
InChI Key InChIKey=HJSUXJIQSLHHPP-LPYMAVHISA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 259854
TargetProto-oncogene tyrosine-protein kinase Src [S345C](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 290nMpH: 7.4 T: 2°CAssay Description:Wild-type and S345C mutant cSrc kinase domains were expressed and purified as described (Blair et al., Nat. Chem. Biol., 2007). The purified cSrc kin...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 70nMT: 2°CAssay Description:Btk (human, full length) was purchased (Invitrogen, catalog number PV3363) and used as specified in the product literature. Btk (2 nM final concentra...More data for this Ligand-Target Pair