BDBM259878 US9505766, 83

SMILES CC(C)(CO)NC(=O)C(=C\c1cccc(c1)-n1cc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12)\C#N

InChI Key InChIKey=IYFRQEQBJKRSLE-HZHRSRAPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 259878   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259878(US9505766, 83)
Affinity DataIC50:  80nMT: 2°CAssay Description:Btk (human, full length) was purchased (Invitrogen, catalog number PV3363) and used as specified in the product literature. Btk (2 nM final concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src [S345C](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259878(US9505766, 83)
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:Wild-type and S345C mutant cSrc kinase domains were expressed and purified as described (Blair et al., Nat. Chem. Biol., 2007). The purified cSrc kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259878(US9505766, 83)
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:Wild-type and S345C mutant cSrc kinase domains were expressed and purified as described (Blair et al., Nat. Chem. Biol., 2007). The purified cSrc kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent