BDBM26134 (4-nonylphenyl)boranediol::Phenylboronic Acid, 13

SMILES CCCCCCCCCc1ccc(cc1)B(O)O

InChI Key InChIKey=VONVJOGSLHAKOX-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 26134   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University of Oxford

LigandPNGBDBM26134((4-nonylphenyl)boranediol | Phenylboronic Acid, 13)
Affinity DataIC50:  9.10nMpH: 7.4 T: 2°CAssay Description:[3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation counting of the aqueous phase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM26134((4-nonylphenyl)boranediol | Phenylboronic Acid, 13)
Affinity DataIC50:  7.90E+3nMAssay Description:The endpoint enzymatic assay was developed to quantify human recombinant MGL activity with 2-AG. The formation of arachidonic acid and depletion of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University of Oxford

LigandPNGBDBM26134((4-nonylphenyl)boranediol | Phenylboronic Acid, 13)
Affinity DataIC50:  2.92E+3nMAssay Description:Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Tufts University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM26134((4-nonylphenyl)boranediol | Phenylboronic Acid, 13)
Affinity DataIC50:  100nMAssay Description:Inhibition of human endothelial lipase overexpressed in HUVEC cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Tufts University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM26134((4-nonylphenyl)boranediol | Phenylboronic Acid, 13)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human endothelial lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Homo sapiens (Human))
Tufts University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM26134((4-nonylphenyl)boranediol | Phenylboronic Acid, 13)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Homo sapiens (Human))
Tufts University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM26134((4-nonylphenyl)boranediol | Phenylboronic Acid, 13)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM26134((4-nonylphenyl)boranediol | Phenylboronic Acid, 13)
Affinity DataIC50:  9.10E+3nMAssay Description:Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed