BDBM262688 3-(2-Aminobenzo[d]thiazol-4-yl)-6- (2-(4-aminocyclohexyl)ethyl)-2-(2H- tetrazol-5-yl)benzenesulfonamide::US9708336, 541

SMILES NC1CCC(CCc2ccc(-c3cccc4sc(N)nc34)c(-c3nn[nH]n3)c2S(N)(=O)=O)CC1

InChI Key InChIKey=IFMLKRYHIGEBQR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262688   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262688(3-(2-Aminobenzo[d]thiazol-4-yl)-6- (2-(4-aminocycl...)
Affinity DataIC50:  7.21nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262688(3-(2-Aminobenzo[d]thiazol-4-yl)-6- (2-(4-aminocycl...)
Affinity DataIC50:  5.11nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262688(3-(2-Aminobenzo[d]thiazol-4-yl)-6- (2-(4-aminocycl...)
Affinity DataIC50:  0.133nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent