BDBM263709 6-(4- ethoxy-2- methyl- phenyl)-1- fluoro-5-[4- [(3S)-1-(3- fluoropropyl)- pyrrolidin-3- yl]oxy- phenyl]-8,9- dihydro- 7H- benzo[7]- annulen-2-ol::US9714221, Example 46

SMILES CCOc1ccc(c(C)c1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)c(F)c2CCC1

InChI Key InChIKey=CXHAXDNLQJNAAM-SANMLTNESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 263709   

TargetEstrogen receptor(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM263709(6-(4- ethoxy-2- methyl- phenyl)-1- fluoro-5-[4- [(...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [Y537S](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM263709(6-(4- ethoxy-2- methyl- phenyl)-1- fluoro-5-[4- [(...)
Affinity DataIC50:  16nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [D538G](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM263709(6-(4- ethoxy-2- methyl- phenyl)-1- fluoro-5-[4- [(...)
Affinity DataIC50:  21nMpH: 7.4 T: 2°CAssay Description:It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent