BDBM274981 N2-(tert-butyl)-N8-(2-(1-methyl-1H- benzo[d]imidazol-2-yl)ethyl)-5-(3- (trifluoromethyl)phenyl)-3,4- dihydroisoquinoline-2,8(1H)-dicarboxamide::US9877957, Example 20

SMILES Cn1c(CCNC(=O)c2ccc(-c3cccc(c3)C(F)(F)F)c3CCN(Cc23)C(=O)NC(C)(C)C)nc2ccccc12

InChI Key InChIKey=VVUDWCKPHYYUGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 274981   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM274981(N2-(tert-butyl)-N8-(2-(1-methyl-1H- benzo[d]imidaz...)
Affinity DataIC50:  205nMpH: 7.0 T: 2°CAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent