BDBM27580 8-[4-(3-chlorophenoxymethyl)phenyl]-8-ethyl-9-oxa-2-azatricyclo[8.4.0.0^{2,6}]tetradeca-1(14),3,5,10,12-pentaen-7-one::Pyrrolobenzoxazepinone (PBO), 5
SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccc(COc2cccc(Cl)c2)cc1
InChI Key InChIKey=TWHRAFICIVSMBQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 27580
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Universita Di Siena
Universita Di Siena
Affinity DataKi: 100nM ΔG°: -9.93kcal/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Universita Di Siena
Universita Di Siena
Affinity DataKi: 250nM ΔG°: -9.36kcal/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Universita Di Siena
Universita Di Siena
Affinity DataKi: 300nM ΔG°: -9.25kcal/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,V767D]/[588-1147,V767D](Human immunodeficiency virus type 1)
Universita Di Siena
Universita Di Siena
Affinity DataKi: 300nMAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,Y769I]/[588-1147,Y769I](Human immunodeficiency virus type 1)
Universita Di Siena
Universita Di Siena
Affinity DataKi: <1.00E+4nM ΔG°: <-7.09kcal/molepH: 7.5 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HIV1 reverse transcriptase V179D mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HIV1 wild type reverse transcriptaseMore data for this Ligand-Target Pair