BDBM28846 2-[(5Z)-5-{[5-(4-bromophenyl)furan-2-yl]methylidene}-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanedioic acid::rhodanine derivative, 5

SMILES OC(=O)CC(N1C(=S)S\C(=C/c2ccc(o2)-c2ccc(Br)cc2)C1=O)C(O)=O

InChI Key InChIKey=KLTFJVAILHPIBO-AUWJEWJLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 28846   

TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM28846(2-[(5Z)-5-{[5-(4-bromophenyl)furan-2-yl]methyliden...)
Affinity DataIC50:  3.98E+3nMpH: 7.4 T: 2°CAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plate in which each reaction mixture contained MAPKKide, LF (List Biological Labor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Nas Of Ukraine

Curated by ChEMBL
LigandPNGBDBM28846(2-[(5Z)-5-{[5-(4-bromophenyl)furan-2-yl]methyliden...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Burnham Institute For Medical Research

LigandPNGBDBM28846(2-[(5Z)-5-{[5-(4-bromophenyl)furan-2-yl]methyliden...)
Affinity DataIC50:  5.16E+4nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plates in which each reaction mixture contained SNAPtide, BoNT /A (List Biological...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed