BDBM293984 (2S)-5-(2-(4-((3-(2-Methyl-4-(3- (methylsulfonyl)propoxy)phenyl) benzo[b]thiophen-5- yl)methoxy)phenyl)pent-3-yn-1- yl)-1H-tetrazole::US10106553, Compound 16
SMILES CC#C[C@@H](Cc1nnn[nH]1)c1ccc(OCc2ccc3scc(-c4ccc(OCCCS(C)(=O)=O)cc4C)c3c2)cc1
InChI Key
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 293984
Affinity DataEC50: 23nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair