BDBM294007 (2S)-5-(2-(4-((2- (Methylsulfonyl)-3-(2- methylphenyl)benzo[b]thiophen- 5-yl)methoxy)phenyl)pent-3- yn-1-yl)-1H-tetrazole::US10106553, Compound 39

SMILES CC#C[C@@H](Cc1nnn[nH]1)c1ccc(OCc2ccc3sc(c(-c4ccccc4C)c3c2)S(C)(=O)=O)cc1

InChI Key

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 294007   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM294007((2S)-5-(2-(4-((2- (Methylsulfonyl)-3-(2- methylphe...)
Affinity DataEC50:  670nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM294007((2S)-5-(2-(4-((2- (Methylsulfonyl)-3-(2- methylphe...)
Affinity DataEC50:  672nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM294007((2S)-5-(2-(4-((2- (Methylsulfonyl)-3-(2- methylphe...)
Affinity DataEC50:  128nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed