BDBM300204 7-(3,3-Difluoropyrrolidin-1-yl)-5-[(2S)-1,1,1-trifluoropropan-2-yl]oxy-3-(3,3,3-trifluoropropyl)triazolo[4,5-d]pyrimidine::US9593123, Example 75

SMILES C[C@H](Oc1nc(N2CCC(F)(F)C2)c2nnn(CCC(F)(F)F)c2n1)C(F)(F)F

InChI Key InChIKey=YTWYAWNPNZGPIY-ZETCQYMHSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300204   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300204(7-(3,3-Difluoropyrrolidin-1-yl)-5-[(2S)-1,1,1-trif...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM300204(7-(3,3-Difluoropyrrolidin-1-yl)-5-[(2S)-1,1,1-trif...)
Affinity DataEC50:  4.30nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent