BDBM300839 2-((1r,3r)-3-Hydroxy-1-(4-((3- (2-methyl-4-((tetrahydro-2H- pyran-4-yl)oxy)phenyl) benzo[b]thiophen-5- yl)methoxy)phenyl)cyclobutyl) acetic acid::US10131648, Compound 37::US10195178, Compound 37::US9790198, Compound 37

SMILES Cc1cc(OC2CCOCC2)ccc1-c1csc2ccc(COc3ccc(cc3)[C@@]3(CC(O)=O)C[C@H](O)C3)cc12

InChI Key InChIKey=SIBRSXNFXBJNDV-KFUJTCAESA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300839   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300839(2-((1r,3r)-3-Hydroxy-1-(4-((3- (2-methyl-4-((tetra...)
Affinity DataEC50:  17nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300839(2-((1r,3r)-3-Hydroxy-1-(4-((3- (2-methyl-4-((tetra...)
Affinity DataEC50:  17nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300839(2-((1r,3r)-3-Hydroxy-1-(4-((3- (2-methyl-4-((tetra...)
Affinity DataEC50:  17nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent