BDBM312684 US9604998, Example 83
SMILES CCOc1cc(CCN2CCN3C[C@H](OC[C@@H]3C2)c2ccc3C(=O)OCc3c2C)ccc1C#N
InChI Key InChIKey=HJJYKOGVJRFZAJ-LVXARBLLSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 312684
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 90nMAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair