BDBM312707 US9604998, Example 106
SMILES Cc1c(ccc(F)c1[N+]#[C-])[C@H]1CN2CCN(CCc3ccc4C(=O)OCc4c3)C[C@@H]2CN1
InChI Key InChIKey=QNEVJOZRAUDJDK-WMZHIEFXSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 312707
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 50nMAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair