BDBM312710 US9604998, Example 109
SMILES Cc1c2COC(=O)c2ccc1[C@@H]1CN2CCN(CC3OCCc4c5COC(=O)c5ccc34)C[C@H]2CO1
InChI Key InChIKey=DAOBVKFRZGSUPI-WFQZMNHWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 312710
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 50nMAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair