BDBM316786 2-[(1-acryloylpiperidin-4-yl)amino]-N-(2,2-difluoropropyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide::US11111242, Example 282::US9617258, Example 282
SMILES CC(F)(F)CNC(=O)c1c[nH]c2ncc(NC3CCN(CC3)C(=O)C=C)nc12
InChI Key InChIKey=WLAXDKMAWDTJIT-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 316786
Affinity DataIC50: 0.200nMAssay Description:Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half log dilution series was created in DMSO...More data for this Ligand-Target Pair
Affinity DataIC50: 12.9nMAssay Description:JAK Caliper Enzyme Assay at 1 mM ATP: Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half l...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:JAK Caliper Enzyme Assay at 4 μM: Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half ...More data for this Ligand-Target Pair
Affinity DataIC50: 12.9nMAssay Description:Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half log dilution series was created in DMSO...More data for this Ligand-Target Pair