BDBM31896 Pyrano[3,2-c]quinoline-6-chlorotacrine hybrid, 21.2HCl

SMILES Clc1ccc(cc1)-c1nc2ccc(cc2c2OCCCc12)C(=O)NCCCCCCCCCNc1c2CCCCc2nc2cc(Cl)ccc12

InChI Key InChIKey=DYQPWUWERYOCLA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 31896   

TargetAcetylcholinesterase(Homo sapiens (Human))
Universitat De Barcelona

LigandPNGBDBM31896(Pyrano[3,2-c]quinoline-6-chlorotacrine hybrid, 21....)
Affinity DataIC50:  24.9nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity was evaluated spectrophotometrically by the method of Ellman, using AChE from bovine or human erythrocytes and acetylthiocho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat De Barcelona

LigandPNGBDBM31896(Pyrano[3,2-c]quinoline-6-chlorotacrine hybrid, 21....)
Affinity DataIC50:  1.39E+3nMAssay Description:BChE inhibitory activity was evaluated spectrophotometrically by the method of Ellman, using BChE from human serum and butyrylthiocholine as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Universitat De Barcelona

LigandPNGBDBM31896(Pyrano[3,2-c]quinoline-6-chlorotacrine hybrid, 21....)
Affinity DataIC50:  24nMpH: 8.0 T: 2°CAssay Description:AChE inhibitory activity was evaluated spectrophotometrically by the method of Ellman, using AChE from bovine or human erythrocytes and acetylthiocho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed