BDBM326944 7-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyridin-3-yl]benzyl}-1,7- diazaspiro[4.4]nonan-2-one::US9662339, 127

SMILES O=C1CCC2(CCN(Cc3ccc(cc3)[C@H]3COc4cccnc4O3)C2)N1

InChI Key InChIKey=UCVLHSWZJIUWKJ-ITUIMRKVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326944   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM326944(7-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyrid...)
Affinity DataIC50:  0.120nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent