BDBM338522 US9751881, Example 52A
SMILES C[C@H]1Cc2cc(ccc2C(=O)O1)C(O)CN1CCC2(CN(C2)c2ccc(cn2)C#N)CC1
InChI Key InChIKey=QDJYQIVQIYJLRS-LBOXEOMUSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 338522
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 48.7nMAssay Description:Assay Protocol: The ROMK channel functional thallium flux assay was performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells were ...More data for this Ligand-Target Pair