BDBM338846 (rac)-N-{3-[4-amino-6-(fluoromethyl)-6,7-dihydro[1,2,3]triazolo[1,5-a]pyrazin-6-yl]-4-fluorophenyl}-5-fluoropyridine-2-carboxamide (compound 9), N-{3-[(6R)-4-amino-6-(fluoromethyl)-6,7-dihydro[1,2,3]triazolo[1,5-a]pyrazin-6-yl]-4-fluorophenyl}-5-fluoropyridine-2-carboxamide (compound 10), N-{3-[(6S)-4-amino-6-(fluoromethyl)-6,7-dihydro[1,2,3]triazolo[1,5-a]pyrazin-6-yl]-4-fluorophenyl}-5-fluoropyridine-2-carboxamide ::US9751886, Compound 11
SMILES NC1=N[C@](CF)(Cn2nncc12)c1cc(NC(=O)c2ccc(F)cn2)ccc1F
InChI Key InChIKey=KTMJHDICOAOUQM-GOSISDBHSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 338846
Affinity DataIC50: 1.00E+9nMAssay Description:This assay is a Fluorescence Resonance Energy Transfer Assay (FRET) based assay. The substrate for this assay is an APP derived 13 amino acids peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 501nMAssay Description:This assay is a Fluorescence Resonance Energy Transfer Assay (FRET) based assay. The substrate for this assay contains the ¿Swedish¿ Lys-Met/Asn-Leu ...More data for this Ligand-Target Pair
Affinity DataIC50: 759nMAssay Description:This assay is a Fluorescence Resonance Energy Transfer Assay (FRET) based assay. The substrate for this assay is an APP derived 13 amino acids peptid...More data for this Ligand-Target Pair