BDBM341632 1-((5R)-5-(4-chloro-2-fluorophenyl)-4a,5-dihydro-thiazolo[2',3':2,3]imidazo[4,5-c]pyridin-6(7H)-yl)-2-(2-chloro-4-morpholinophenoxy)ethanone::US9765092, Example 6.4.2
SMILES Fc1cc(Cl)ccc1[C@@H]1C2N3C=CSC3=NC2=CCN1C(=O)COc1ccc(cc1Cl)N1CCOCC1
InChI Key InChIKey=PBHSGICFDXAPOM-IKOFQBKESA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 341632
Affinity DataIC50: 4nMAssay Description:To generate the enzyme, full length human TPH1 is cloned into the plasmid pET20b(+) (Novagen) and expressed in E. coli. The bacterial cells are ruptu...More data for this Ligand-Target Pair