BDBM342598 N-[3-(2,3-dimethyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1-yl)-4-phenoxyphenyl]methanesulfonamide::US9776990, Example 41

SMILES Cc1c2c(CCCC2=O)c(-c2cc(NS(C)(=O)=O)ccc2Oc2ccccc2)n1C

InChI Key InChIKey=IPNOJAZMRYGFBZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342598   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM342598(N-[3-(2,3-dimethyl-4-oxo-4,5,6,7-tetrahydro-2H-iso...)
Affinity DataKi:  161nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM342598(N-[3-(2,3-dimethyl-4-oxo-4,5,6,7-tetrahydro-2H-iso...)
Affinity DataKi:  216nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent