BDBM342621 N-[3-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1-yl)phenyl]methanesulfonamide::US9776990, Example 64

SMILES Cc1[nH]c(c2CC(C)(C)CC(=O)c12)-c1cccc(NS(C)(=O)=O)c1

InChI Key InChIKey=FXDDTMBJHBDSRS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342621   

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM342621(N-[3-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-2H-...)
Affinity DataKi:  409nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM342621(N-[3-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-2H-...)
Affinity DataKi:  576nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent