BDBM342647 5-[4-(2-Phenoxy-acetyl)-piperazin-1-ylmethyl]-thiophene-2-carboxylic acid 2-trifluoromethyl-benzylamide::US9776991, Example 17

SMILES FC(F)(F)c1ccccc1CNC(=O)c1ccc(CN2CCN(CC2)C(=O)COc2ccccc2)s1

InChI Key InChIKey=NCPBKZUEWKSUIR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342647   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM342647(5-[4-(2-Phenoxy-acetyl)-piperazin-1-ylmethyl]-thio...)
Affinity DataIC50:  0.699nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent