BDBM342691 5-[4-(2-Hydroxy-propionyl)-piperazin-1-ylmethyl]-thiophene-2-carboxylic acid 2-chloro-4-cyano-benzylamide::US9776991, Example 61

SMILES CC(O)C(=O)N1CCN(Cc2ccc(s2)C(=O)NCc2ccc(cc2Cl)C#N)CC1

InChI Key InChIKey=BOJPFEQXZOXWCG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342691   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM342691(5-[4-(2-Hydroxy-propionyl)-piperazin-1-ylmethyl]-t...)
Affinity DataIC50:  1.18nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent