BDBM354738 Preparation of 4-(5-(3,4,5-trimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)aniline ::US10485800, Example 15::US9814704, Example 15

SMILES COc1cc(cc(OC)c1OC)-c1cnc2[nH]cc(-c3ccc(N)cc3)c2c1

InChI Key InChIKey=WHSSNVULTAFEGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354738   

TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University of Rochester

US Patent
LigandPNGBDBM354738(Preparation of 4-(5-(3,4,5-trimethoxyphenyl)-1H-py...)
Affinity DataIC50: <100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University of Rochester

US Patent
LigandPNGBDBM354738(Preparation of 4-(5-(3,4,5-trimethoxyphenyl)-1H-py...)
Affinity DataIC50: <100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent