BDBM354762 Preparation of 4-(2-(4-(7-(1H-indol-5-yl)-5H-pyrrolo[3,2-b]pyrazin-2-yl)-2-methoxyphenoxy)ethyl)morpholine ::US10485800, Example 39::US9814704, Example 39
SMILES COc1cc(ccc1OCCN1CCOCC1)-c1cnc2[nH]cc(-c3ccc4[nH]ccc4c3)c2n1
InChI Key InChIKey=NVHODTIQMIMBRH-DYTRJAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 354762
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University of Rochester
US Patent
The University of Rochester
US Patent
Affinity DataIC50: <100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University of Rochester
US Patent
The University of Rochester
US Patent
Affinity DataIC50: <100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair