BDBM35873 5,6-bis(4-chlorophenyl)-N-(piperidin-1-yl)pyrazine-2-carboxamide::5,6-bis-(4-chloro-phenyl)-pyrazine-2-carboxylic acidpiperidin-1-ylamide::5,6-diaryl-pyrazine-2-amide derivative, 5e::CHEMBL390146

SMILES Clc1ccc(cc1)-c1ncc(nc1-c1ccc(Cl)cc1)C(=O)NN1CCCCC1

InChI Key InChIKey=FBMFLCCMSCORDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35873   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM35873(5,6-bis(4-chlorophenyl)-N-(piperidin-1-yl)pyrazine...)
Affinity DataIC50:  8.13nMAssay Description:Antagonist activity against human recombinant cannabinoid-1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM35873(5,6-bis(4-chlorophenyl)-N-(piperidin-1-yl)pyrazine...)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed