BDBM359586 4-{(6R or S)-1-({2- chloro-6-[1- (trifluoromethyl)cyclo- propyl]phenyl}car- bonyl)-6-[(3- hydroxyazetidin-1- yl)carbonyl]-4,5,6,7- tetrahydro-1H- indazol-3-yl}-3- fluorobenzoic acid::US10221142, Example 21AAA
SMILES OC1CN(C1)C(=O)C1CCc2c(C1)n(nc2-c1ccc(cc1F)C(O)=O)C(=O)c1c(Cl)cccc1C1(CC1)C(F)(F)F
InChI Key InChIKey=DCNGQFJUAZAGPU-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 359586
Affinity DataIC50: 0.800nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair