BDBM363483 4-(9-(2-hydroxy-2-(2-methyl-6- (1H-tetrazol-1-yl)pyridin-3- yl)ethyl)-1-oxa-4,9- diazaspiro[5.5]undecan-4-yl)-3- methylfuran-2(5H)-one (single diastereomer, absolute stereochemistry not established)::US9850245, Example 22A::US9850245, Example 22B
SMILES CC1=C(COC1=O)N1CCOC2(CCN(CC(O)c3ccc(nc3C)-n3cnnn3)CC2)C1
InChI Key InChIKey=WVRMJKIGUCYMPF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 363483
Affinity DataIC50: 29nMAssay Description:Blocking of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Blocking of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks...More data for this Ligand-Target Pair