BDBM366680 4-[[8-[4-(4- chlorophenyl)-4- (hydroxymethyl)-1- piperidyl]- [1,2,4]triazolo[1,5- a]pyridin-2-yl]amino]- N-[2-[(2S,6S)-2,6- dimethylmorpholin-4- yl]ethyl]benzamide::US9873709, Example 1-277
SMILES C[C@H]1CN(CCNC(=O)c2ccc(Nc3nc4c(cccn4n3)N3CCC(CO)(CC3)c3ccc(Cl)cc3)cc2)C[C@H](C)O1
InChI Key InChIKey=HMPBTTNGSDGQNT-ZEQRLZLVSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 366680
Affinity DataKi: 0.240nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair