BDBM366692 2-[4-[[8-[4-(4- chlorophenyl)-4- (hydroxymethyl)-1- piperidyl]- [1,2,4]triazolo[1,5- a]pyridin-2- yl]amino]pyrazol-1- yl]-1-[4- (morpholinomethyl)- 1-piperidyl]ethanone::US9873709, Example 1-289
SMILES OCC1(CCN(CC1)c1cccn2nc(Nc3cnn(CC(=O)N4CCC(CN5CCOCC5)CC4)c3)nc12)c1ccc(Cl)cc1
InChI Key InChIKey=SYYUHYLLYOEPEF-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 366692
Affinity DataKi: 0.260nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Affinity DataKi: 0.420nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair