BDBM385393 4-((R or S)-6-(azetidine- 1-carbonyl)-1-(2- chloro-6- cyclopropylbenzoyl)- 4,5,6,7-tetrahydro-1H- indazol-3-yl)cyclohex- 3-ene-1-carboxylic acid::US10287272, Example 2B::US10689369, Example 2B
SMILES OC(=O)C1CCC(=CC1)c1nn(C(=O)c2c(Cl)cccc2C2CC2)c2CC(CCc12)C(=O)N1CCC1
InChI Key InChIKey=PYVIDPJYTUEDEX-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 385393
Affinity DataIC50: 2nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair