BDBM385504 (R or S)-4-((R or S)-1- (2-chloro-6-(1- (trifluoromethyl)cyclo- propyl)benzoyl)-6-(3- hydroxyazetidine-1- carbonyl)-4,5,6,7- tetrahydro-1H- indazol-3- yl)cyclohex-3-ene-1- carboxylic acid::US10287272, Example 6N::US10689369, Example 6N
SMILES OC1CN(C1)C(=O)C1CCc2c(C1)n(nc2C1=CCC(CC1)C(O)=O)C(=O)c1c(Cl)cccc1C1(CC1)C(F)(F)F
InChI Key InChIKey=ABKDPJYLDMZBHF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 385504
Affinity DataIC50: 1nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair