BDBM385543 US10287278, Example 5::US10647706, Example 5
SMILES CN=S(C)(=O)c1c(Cl)ccc(Nc2c(N[C@H]([C@H]3CCCS3)c3ccc(C)o3)c(=O)c2=O)c1O
InChI Key InChIKey=YCVBZPNHMVRBPN-AZFZMOAFSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 385543
Affinity DataIC50: >20nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors is determined on a functional test of β-arrest...More data for this Ligand-Target Pair
Affinity DataIC50: <200nMAssay Description:To evaluate the direct interaction of the CXCR2 or CXCR1 receptor with β-arrestin 2, a test of β-arrestin 2 recruitment for CXCR2 or CXCR1 ...More data for this Ligand-Target Pair
Affinity DataIC50: >20nMAssay Description:To evaluate the direct interaction of the CXCR2 or CXCR1 receptor with β-arrestin 2, a test of β-arrestin 2 recruitment for CXCR2 or CXCR1 ...More data for this Ligand-Target Pair
Affinity DataIC50: <200nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors is determined on a functional test of β-arrest...More data for this Ligand-Target Pair