BDBM391738 N-(3-((2-((2-acetyl-8-methoxy-1,2,3,4-tetrahydroisoquinoline-7-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide ::US10300058, Compound 17

SMILES COc1c(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)ccc2CCN(Cc12)C(C)=O

InChI Key InChIKey=KDFJJNDCCSIGGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 391738   

TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM391738(N-(3-((2-((2-acetyl-8-methoxy-1,2,3,4-tetrahydrois...)
Affinity DataIC50:  1.60E+4nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM391738(N-(3-((2-((2-acetyl-8-methoxy-1,2,3,4-tetrahydrois...)
Affinity DataIC50:  1.37E+6nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent