BDBM391740 N-(3-((2-((4-(1-(3-fluoropropionyl)piperidin-4-yl)-2-methoxyphenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide ::US10300058, Compound 25

SMILES COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)C1CCN(CC1)C(=O)CCF

InChI Key InChIKey=UEHPBAFYFOFYLA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 391740   

TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM391740(N-(3-((2-((4-(1-(3-fluoropropionyl)piperidin-4-yl)...)
Affinity DataIC50:  7.10E+3nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM391740(N-(3-((2-((4-(1-(3-fluoropropionyl)piperidin-4-yl)...)
Affinity DataIC50:  6.83E+5nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent