BDBM394161 5-[5-chloro-2- (1H-tetrazol- 1-yl)phenyl]- 2-[(1S)-1-{3- [1-(oxetan-2- ylcarbonyl) piperidin-4- yl]phenyl}-2- phenylethyl] pyridine 1- oxide::US9975874, Example 35
SMILES Clc1ccc(c(c1)-c1ccc([nH+]c1)[C@@H](Cc1ccccc1)c1cccc(c1)C1CCN(CC1)C(=O)C1CCO1)-n1cnnn1
InChI Key InChIKey=FGNYZFBGTYKJNE-LUWJBUJKSA-O
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 394161
Affinity DataIC50: 403nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Kallikrein can be determined using a relevant purified serine protease, a...More data for this Ligand-Target Pair
Affinity DataIC50: 12.2nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair