BDBM397118 N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-1-(5-methyl-2-thiazolyl)-6-oxo-3-pyridinecarboxamide::US10456385, Example 11::US9987259, Example 11
SMILES Cc1cnc(s1)-n1cc(ccc1=O)C(=O)N[C@H]1CN2CCC1CC2
InChI Key InChIKey=MVVOOXHHBAOIKY-AWEZNQCLSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 397118
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals
US Patent
Sk Biopharmaceuticals
US Patent
Affinity DataEC50: <100nMAssay Description:Activity of heteromeric α7 nAChR was measured via FlexStation-Ca2+ influx assay. In the present example, in consideration of α7 nAChR being...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Sk Biopharmaceuticals
US Patent
Sk Biopharmaceuticals
US Patent
Affinity DataEC50: <100nMAssay Description:On the day of the assay, after removal of the growth media, the cells were washed once with an assay buffer (7 mM Tris-Cl, 20 mM HEPES, 20 mM NaCl, 5...More data for this Ligand-Target Pair