BDBM402059 N-{2-[(4, 6-dimethylpyrimidin-2- yl)(methyl)amino]ethyl}-N-ethyl-2- (2,2,2-trifluoroethoxy)-benzamide::US10011595, B-17

SMILES CCN(CCN(C)c1nc(C)cc(C)n1)C(=O)c1ccccc1OCC(F)(F)F

InChI Key InChIKey=XQCHKDHNDRGQAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 402059   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402059(N-{2-[(4, 6-dimethylpyrimidin-2- yl)(methyl)amino]...)
Affinity DataIC50:  2.03E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402059(N-{2-[(4, 6-dimethylpyrimidin-2- yl)(methyl)amino]...)
Affinity DataIC50:  11.2nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent