BDBM402084 N-(2-{[4-chloro-6- (dimethylamino)pyrimidin- 2-yl](methyl)amino}ethyl)- N-ethyl-2-(2H-1,2,3-triazol- 2-yl)benzamide::US10011595, E-11

SMILES CCN(CCN(C)c1nc(Cl)cc(n1)N(C)C)C(=O)c1ccccc1-n1nccn1

InChI Key InChIKey=UFKACZUVRSPVOK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 402084   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402084(N-(2-{[4-chloro-6- (dimethylamino)pyrimidin- 2-yl]...)
Affinity DataIC50:  1.15E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402084(N-(2-{[4-chloro-6- (dimethylamino)pyrimidin- 2-yl]...)
Affinity DataIC50:  18.4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent