BDBM402111 N-{2-[(4-cyanopyridin-2- yl)(methyl)amino]ethyl}-N- ethyl-2-(3-methyl-1,2,4- oxadiazol-5-yl)benzamide::US10011595, F-27

SMILES CCN(CCN(C)c1cc(ccn1)C#N)C(=O)c1ccccc1-c1nc(C)no1

InChI Key InChIKey=KNKPQQFJDBLJHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 402111   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402111(N-{2-[(4-cyanopyridin-2- yl)(methyl)amino]ethyl}-N...)
Affinity DataIC50:  8.36E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402111(N-{2-[(4-cyanopyridin-2- yl)(methyl)amino]ethyl}-N...)
Affinity DataIC50:  24nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent