BDBM402128 2-(2,2-difluoroethoxy)-N- ethyl-N-(2-((4-(2- hydroxypropan-2- yl)pyrimidin-2- yl)(methyl)amino)ethyl) nicotinamide::US10011595, H-17

SMILES CCN(CCN(C)c1nccc(n1)C(C)(C)O)C(=O)c1cccnc1OCC(F)(F)F

InChI Key InChIKey=VSUWHVJCEFGMCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 402128   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402128(2-(2,2-difluoroethoxy)-N- ethyl-N-(2-((4-(2- hydro...)
Affinity DataIC50:  1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402128(2-(2,2-difluoroethoxy)-N- ethyl-N-(2-((4-(2- hydro...)
Affinity DataIC50:  21.7nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent