BDBM406106 215-(3-(trans-2'-hydroxy-2',3'- dihydrospiro[cyclopropane- 1,1'-inden]-3'-yl)ureido)-N,4- dimethyl-1-phenyl-1H- pyrazole-3-carboxamide::US10351575, Example 59

SMILES CNC(=O)c1nn(c(NC(=O)NC2[C@H](O)C3(CC3)c3ccccc23)c1C)-c1ccccc1

InChI Key InChIKey=TUDGKYXZGMHGNY-ANYOKISRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406106   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM406106(215-(3-(trans-2'-hydroxy-2',3'- dihydrospiro[cyclo...)
Affinity DataIC50: <100nMAssay Description:TrkA binding activity was determined in a TrkA LanthaScreen™ Eu Kinase Binding Assay. 5 nM His-tagged recombinant human TrkA (6HIS tagged cytoplasmic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent