BDBM413426 (S)-2-morpholino-2-oxoethyl 2-(4-((2-amino-4-((1-hydroxyhexan-2-yl)amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl)methyl)-3-methoxyphenyl)acetate::US10407431, Example 13

SMILES CCCC[C@@H](CO)Nc1nc(N)nc2ccn(Cc3ccc(CC(=O)OCC(=O)N4CCOCC4)cc3OC)c12

InChI Key InChIKey=WFCIVSVAGXYJEZ-NRFANRHFSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413426   

TargetToll-like receptor 7(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM413426((S)-2-morpholino-2-oxoethyl 2-(4-((2-amino-4-((1-h...)
Affinity DataEC50:  10nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent