BDBM416640 US10323013, Compound 23::allyl 8-hydroxy-7-chloro-5-oxo-4,5-dihydro-1H-chromeno[3,4-c]pyridine-3(2H)-carboxylate

SMILES Oc1ccc2c3CCN(Cc3c(=O)oc2c1Cl)C(=O)OCC=C

InChI Key InChIKey=RYOOEDORAWJBSO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 416640   

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM416640(US10323013, Compound 23 | allyl 8-hydroxy-7-chloro...)
Affinity DataIC50: >2.00E+4nMAssay Description:All compounds were evaluated by FRET-suppression assay in side-by-side experiments using 21b as a control inhibitor (Table 2). Protection of the alde...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent